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- 2024
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Muccio S, Hirtz C, Descloux S, Fedeli O, Macé S, Lehmann S, Vialaret J. A sensitive high-resolution mass spectrometry method for quantifying intact M-protein light chains in patients with multiple myeloma. Clin Chim Acta. 2024 Jan 1;552:117634. doi: 10.1016/j.cca.2023.117634. Epub 2023 Nov 20 Nov 20. PubMed PMID: 37980975Read More
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Gouyon J, Clavié M, Raquel G-C, Ngo G, Dumy P, Etienne P, Martineau P, Pugnière M, Ahmad M, Subra G, Perrin C, Ladner Y. A bioinspired approach for the modulation of electroosmotic flow and protein–surface interactions in capillary electrophoresis using silylated amino-amides blocks and covalent grafting. Electrophoresis. 2024 Mar;45(5-6):557-572. doi: 10.1002/elps.202300168. Epub 2023 Dec 31 PubMed PMID: 38161236Read More
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Esposito F, Sinquin C, Colliec-Jouault S, Cuenot S, Pugnière M, Ngo G, Traboni S, Zykwinska A, Bedini E. Multi-step semi-synthesis, structural characterization and growth factor interaction study of regiochemically sulfated diabolican polysaccharides. Int J Biol Macromol. 2024 Mar;260(Pt 1):129483. doi: 10.1016/j.ijbiomac.2024.129483. Epub 2024 Jan 17. PMID: 38242385Read More
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Philibert CE, Disdier C, Lafon PA, Bouyssou A, Oosterlaken M, Galant S, Pizzoccaro A, Tuduri P, Ster J, Liu J, Kniazeff J, Pin JP, Rondard P, Marin P, Vandermoere F. TrkB receptor interacts with mGlu2 receptor and mediates antipsychotic-like effects of mGlu2 receptor activation in the mouse. Sci Adv. 2024 Jan 26;10(4):eadg1679. doi: 10.1126/sciadv.adg1679. Epub 2024 Jan 26. PMCID: PMC10816717. PubMed PMID: 38277461Read More
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Desroys du Roure P, Lajoie L, Mallavialle A, Alcaraz LB, Mansouri H, Fenou L, Garambois V, Rubio L, David T, Coenon L, Boissière-Michot F, Chateau MC, Ngo G, Jarlier M, Villalba M, Martineau P, Laurent-Matha V, Roger P, Guiu S, Chardès T, Gros L, Liaudet-Coopman E. A novel Fc-engineered cathepsin D-targeting antibody enhances ADCC, triggers tumor-infiltrating NK cell recruitment, and improves treatment with paclitaxel and enzalutamide in triple-negative breast cancer. J Immunother Cancer. 2024 Jan 30;12(1):e007135. doi: 10.1136/jitc-2023-007135. PMID: 38290768Read More
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Aze A, Hutchins JRA, Maiorano D. Studying Translesion DNA Synthesis Using Xenopus In Vitro Systems. Methods Mol Biol. 2024;2740:21-36. doi: 10.1007/978-1-0716-3557-5_2. PMID: 38393467Read More
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Mohaupt P, Vialaret J, Hirtz C, Lehmann S. Increasing the sensitivity of Simoa via bead count reduction facilitates the quantification of pTau-181 in dried plasma spots. Alzheimers Dement (N Y). 2024 Mar 11;10(1):e12456. doi: 10.1002/trc2.12456. PMID: 38476928Read More
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Soha Salloum, Martial Séveno, Khadija El Koulali, Stephanie Rialle, Simon George, Benedicte Lemmers, Kazem Zibara, Carolina Eliscovich, Michael Hahne, Edouard Bertrand Co-translational sorting enables a single mRNA to generate distinct polysomes with different localizations and protein fates BioXriv. 2024 March 20 DOI: 10.1101/2024.03.20.58588120Read More
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Beauchet A, Bollier N, Grison M, Rofidal V, Gévaudant F, Bayer E, Gonzalez N, Chevalier C The CELL NUMBER REGULATOR FW2.2 protein regulates cell-to-cell communication in tomato by modulating callose deposition at plasmodesmata Plant Physiol. 2024 Apr 8:kiae198. doi: 10.1093/plphys/kiae198. Epub ahead of print. PMID: 38588030Read More
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Hinsinger G, Du Trieu De Terdonck L, Urbach S, Salvetat N, Rival M, Galoppin M, Ripoll C, Cezar R, Laurent-Chabalier S, Demattei C, Agherbi H, Castelnovo G, Lehmann S, Rigau V, Marin P, Thouvenot E. CD138 as a Specific CSF Biomarker of Multiple Sclerosis Neurol Neuroimmunol Neuroinflamm. 2024 May;11(3):e200230. doi: 10.1212/NXI.0000000000200230. PMID: 38669615Read More
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Masmoudi D, Vialaret J, Hirtz C, Alix-Panabières C. Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells. Mol Oncol. 2024 May 22. doi: 10.1002/1878-0261.13665. Epub ahead of print. PMID: 38775116Read More
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Diagouraga B, Tambones I, Carivenc C, Bechara C, Nadal M, de Massy B, le Maire A, Robert T The TOPOVIBL meiotic DSB formation protein: new insights from its biochemical and structural characterization Nucleic Acids Res. 2024 Jul 5:gkae587. doi: 10.1093/nar/gkae587. Epub ahead of print. PMID: 38966985Read More
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Giroux P, Vialaret J, Kindermans J, Gabelle A, Bauchet L, Hirtz C, Lehmann S, Colinge J. Modeling the Simultaneous Dynamics of Proteins in Blood Plasma and the Cerebrospinal Fluid in Human In Vivo. J Proteome Res. 2024 Jul 5;23(7):2408-2418. doi: 10.1021/acs.jproteome.4c00059. Epub 2024 Jun 10. PMID: 38857467Read More
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Issa A, Schlotter F, Flayac J, Chen J, Wacheul L, Philippe M, Sardini L, Mostefa L, Vandermoere F, Bertrand E, Verheggen C, Lafontaine DL, Massenet S. The nucleolar phase of signal recognition particle assembly Life Sci Alliance. 2024 Jun 10;7(8):e202402614. doi: 10.26508/lsa.202402614. PMID: 38858088Read More
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Alessandro Rabbito, Omolade Otun, Amos Fumagalli, Martial Séveno, Sonya Galant, Manuel Counson, Thierry Durroux, Cherine Bechara, Martine J Smit, Sébastien Granier, Martyna Szpakowska, Andy Chevigné, Séverine Chaumont-Dubel, Philippe Marin Physical interaction with Ephrin B1 promotes CXCR4 intracellular localization and oncogenic potential BioXriv. 2024 July 11 DOI: 10.1101/2024.07.10.602459Read More
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Boyer JC, Véry AA, Fristot E, Guyot V, Sentenac H, Peltier JB Cell-free expressed uniporter and symporter systems from the plant HKT transporter family display channel-like gating and unitary conductances. New Phytol. 2024 Sep;243(5):1651-1657. doi: 10.1111/nph.19958. Epub 2024 Jul 11. PMID: 38992953.Read More
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Otun O, Aljamous C, Del Nero E, Arimont-Segura M, Bosma R, Zarzycka B, Girbau T, Leyrat C, de Graaf C, Leurs R, Durroux T, Granier S, Cong X, Bechara C. Conformational dynamics underlying atypical chemokine receptor 3 activation Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2404000121. doi: 10.1073/pnas.2404000121. Epub 2024 Jul 15. PMID: 39008676Read More
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Coënon L, Rigal E, Courot H, Multrier C, Zemiti S, Lambour J, Pugnière M, de Toledo M, Bossis G, Cartron G, Robert B, Martineau P, Fauvel B, Presumey J, Villalba M. Generation of non-genetically modified, CAR-like, NK cells J Immunother Cancer. 2024 Jul 18;12(7):e009070. doi: 10.1136/jitc-2024-009070. PMID: 39029925Read More
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Lehmann S, Vialaret J, Gabelle A, Bauchet L, Villemin JP, Hirtz C, Colinge J. Enabling population protein dynamics through Bayesian modeling. Bioinformatics. 2024 Aug 2;40(8):btae484. doi: 10.1093/bioinformatics/btae484. PMID: 39078204Read More
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Meneux L, Feret N, Pernot S, Girard M, Sarkis S, Caballero Megido A, Quiles M, Müller A, Fichter L, Vialaret J, Hirtz C, Delettre C, Michon F. Inherited mitochondrial dysfunction triggered by OPA1 mutation impacts the sensory innervation fibre identity, functionality and regenerative potential in the cornea. Sci Rep. 2024 Aug 13;14(1):18794. doi: 10.1038/s41598-024-68994-4. PMID: 39138286Read More
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Maclean AE, Sloan MA, Renaud EA, Argyle BE, Lewis WH, Ovciarikova J, Demolombe V, Waller RF, Besteiro S, Sheiner L The Toxoplasma gondii mitochondrial transporter ABCB7L is essential for the biogenesis of cytosolic and nuclear iron-sulfur cluster proteins and cytosolic translation mBio. 2024 Aug 29:e0087224. doi: 10.1128/mbio.00872-24. Epub ahead of print. PMID: 39207139Read More
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Truffinet F, Arco-Hierves A, Shalabi H, Pascaud J, Mazet P, Rivière E, E Silva-Saffar S, Fabbri L, Leboucher S, Besse L, Messaoudi C, Attina A, David A, Vagner S, Nocturne G, Mariette X, Bechara R. m6A RNA methylation controls salivary gland epithelial cell function and has a protective role in Sjögren's disease. Ann Rheum Dis. 2024 Sep 25:ard-2024-226224. doi: 10.1136/ard-2024-226224. Epub ahead of print. PMID: 39299724.Read More
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Boulay A, Quevarec E, Malet I, Nicastro G, Chamontin C, Perrin S, Henriquet C, Pugnière M, Courgnaud V, Blaise M, Marcelin AG, Taylor IA, Chaloin L, Arhel NJ. A new class of capsid-targeting inhibitors that specifically block HIV-1 nuclear import. EMBO Mol Med. 2024 Oct 2. doi: 10.1038/s44321-024-00143-w. Online ahead of print. PMID: 39358603Read More
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Fouillen A, Couvineau P, Gaibelet G, Riché S, Orcel H, Mendre C, Kanso A, Lanotte R, Nguyen J, Dimon J, Urbach S, Sounier R, Granier S, Bonnet D, Cong X, Mouillac B, Déméné H Biased activation of the vasopressin V2 receptor probed by molecular dynamics simulations, NMR and pharmacological studies Comput Struct Biotechnol J 2024 Oct 23 doi : 10.1016/j.csbj.2024.10.039 PMID: 39525085Read More
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Abéza C, Busse P, Paiva ACF, Chagot ME, Schneider J, Robert MC, Vandermoere F, Schaeffer C, Charpentier B, M F Sousa P, Bandeiras TM, Manival X, Cianferani S, Bertrand E, Verheggen C The HSP90/R2TP quaternary chaperone scaffolds assembly of the TSC complex J Mol Biol. 2024 Oct 26:168840. doi: 10.1016/j.jmb.2024.168840. PMID: 39490680Read More
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Leipp F, Vialaret J, Mohaupt P, Coppens S, Jaffuel A, Niehoff AC, Lehmann S, Hirtz C. Glial fibrillary acidic protein in Alzheimer's disease: a narrative review. Brain Commun. 2024 Nov 7;6(6):fcae396. doi: 10.1093/braincomms/fcae396. PMID: 39554381Read More
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Khong MT, Darcos V, Vialaret J, Ng F, Couture G, Cagnon ME, L Noriega A, Kindermans J, Garric X, Hirtz C, Nottelet B. Ultrasensitive In Vitro and Ex Vivo Tracking of 13C-Labeled PEG-PLA Degradation Products by MALDI-TOF Mass Spectrometry. Biomacromolecules. 2024 Nov 11;25(11):7485-7499. doi: 10.1021/acs.biomac.4c01169. PMID: 39441127.Read More
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Moussa DA, Vazquez M, Chable-Bessia C, Roux-Portalez V, Tamagnini E, Pedotti M, Simonelli L, Ngo G, Souchard M, Lyonnais S, Chentouf M, Gros N, Marsile-Medun S, Dinter H, Pugnière M, Martineau P, Varani L, Juan M, Calderon H, Naranjo-Gomez M, Pelegrin M. Discovery of a pan anti-SARS-CoV-2 monoclonal antibody with highly efficient infected cell killing capacity for novel immunotherapeutic approaches. Emerg Microbes Infect. 2024 Nov 25:2432345. doi: 10.1080/22221751.2024.2432345. Epub ahead of print PMID: 39584380Read More
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Maria Vittoria Modica, Serena Leone, Marco Gerdol, Samuele Greco, Didier Aurelle, Marco Oliverio, Giulia Fassio, Khadija El Koulali, Célia Barrachina, Sebastien Dutertre The proteotranscriptomic characterization of venom in the white seafan Eunicella singularis elucidates the evolution of Octocorallia arsenal BioRxiv 2024 November 30 doi: 10.1101/2024.05.31.596435Read More
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Damodar K, Dubois G, Guillou L, Mamaeva D, Pequignot M, Erkilic N, Sanjurjo-Soriano C, Boukhaddaoui H, Bernex F, Bocquet B, Vialaret J, Arsenijevic Y, Redmond TM, Hirtz C, Meunier I, Brabet P, Kalatzis V. Dual CRALBP isoforms unveiled: iPSC-derived retinal modeling and AAV2/5-RLBP1 gene transfer raise considerations for effective therapy. Mol Ther. 2024 Dec 4 doi: 10.1016/j.ymthe.2024.10.004. PMID: 39385467Read More
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Amalric A, Attina A, Bastide A, Buffard M, Mateus S, Planque C, Rivals E, Hirtz C, David A. Mass Spectrometry-Based Pipeline for Identifying RNA Modifications Involved in a Functional Process: Application to Cancer Cell Adaptation Anal Chem. 2024 Feb 6;96(5):1825-1833. doi: 10.1021/acs.analchem.3c02635. Epub 2024 Jan 26. PubMed PMID: 38275837Read More
