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Berger N, Demolombe V, Hem S, Rofidal V, Steinmann L, Krouk G, Crabos A, Nacry P, Verdoucq L, Santoni V. Root Membrane Ubiquitinome under Short-Term Osmotic Stress. Int J Mol Sci. 2022 Feb 10;23(4):1956. doi: 10.3390/ijms23041956. PubMed PMID: 35216074Read More
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Hirtz C, Mannaa AM, Moulis E, Pible O, O'Flynn R, Armengaud J, Jouffret V, Lemaistre C, Dominici G, Martinez AY, Dunyach-Remy C, Tiers L, Lavigne JP, Tramini P, Goldsmith MC, Lehmann S, Deville de Périère D, Vialaret J. Deciphering Black Extrinsic Tooth Stain Composition in Children Using Metaproteomics. ACS Omega. 2022 Feb 25;7(10):8258-8267. doi: 10.1021/acsomega.1c04770. PubMed PMID: 35309464Read More
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Cesari S, Xi Y, Declerck N, Chalvon V, Mammri L, Pugnière M, Henriquet C, de Guillen K, Chochois V, Padilla A, Kroj T. New recognition specificity in a plant immune receptor by molecular engineering of its integrated domain. Nat Commun. 2022 Mar 21;13(1):1524. doi: 10.1038/s41467-022-29196-6. PubMed PMID: 35314704Read More
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Eichholz K, Tran TH, Chéneau C, Tran TTP, Paris O, Pugniere M, Kremer EJ. Adenovirus-α-Defensin Complexes Induce NLRP3-Associated Maturation of Human Phagocytes via Toll-Like Receptor 4 Engagement. J Virol. 2022 Mar 23;96(6):e0185021. doi: 10.1128/jvi.01850-21. Epub 2022 Jan 26. PubMed PMID: 35080426Read More
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Pons ML, Loftus N, Vialaret J, Moreau S, Lehmann S, Hirtz C. Proteomics Challenges for the Assessment of Synuclein Proteoforms as Clinical Biomarkers in Parkinson's Disease. Front Aging Neurosci. 2022 Mar 31;14:818606. doi: 10.3389/fnagi.2022.818606. PubMed PMID: 35431896Read More
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Sengupta S, Mondal M, Prasasvi KR, Mukherjee A, Magod P, Urbach S, Friedmann-Morvinski D, Marin P, Somasundaram K. Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth. Elife. 2022 Jun 1;11:e78972. doi: 10.7554/eLife.78972. PubMed PMID: 35642785Read More
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Koua D, Ebou A, Habbouche Z, Ballouard JM, Caron S, Bonnet X, Dutertre S. Proteomic insight into the venom composition of the largest European rear-fanged snake, Malpolon monspessulanus monspessulanus. Toxicon X. 2022 Jun 10;15:100130. doi: 10.1016/j.toxcx.2022.100130. PubMed PMID: 35721600Read More
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Rebendenne A, Roy P, Bonaventure B, Chaves Valadão AL, Desmarets L, Arnaud-Arnould M, Rouillé Y, Tauziet M, Giovannini D, Touhami J, Lee Y, DeWeirdt P, Hegde M, Urbach S, Koulali KE, de Gracia FG, McKellar J, Dubuisson J, Wencker M, Belouzard S, Moncorgé O, Doench JG, Goujon C. Bidirectional genome-wide CRISPR screens reveal host factors regulating SARS-CoV-2, MERS-CoV and seasonal HCoVs. Nat Genet. 2022 Aug;54(8):1090-1102. doi: 10.1038/s41588-022-01110-2. Epub 2022 Jul 25. PubMed PMID: 35879413Read More
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Relier S, Amalric A, Attina A, Koumare IB, Rigau V, Burel Vandenbos F, Fontaine D, Baroncini M, Hugnot JP, Duffau H, Bauchet L, Hirtz C, Rivals E, David A. Multivariate Analysis of RNA Chemistry Marks Uncovers Epitranscriptomics-Based Biomarker Signature for Adult Diffuse Glioma Diagnostics. Anal Chem. 2022 Sep 6;94(35):11967-11972. doi: 10.1021/acs.analchem.2c01526. Epub 2022 Aug 23. PubMed PMID: 35998076Read More
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Fayd'herbe De Maudave A, Leconet W, Toupet K, Constantinides M, Bossis G, de Toledo M, Vialaret J, Hirtz C, Lopez-Noriega A, Jorgensen C, Noël D, Louis-Plence P, Grizot S, Villalba M. Intra-articular delivery of full-length antibodies through the use of an in situ forming depot. J Control Release. 2022 Jan;341:578-590. doi: 10.1016/j.jconrel.2021.12.010. Epub 2021 Dec 13. PubMed PMID: 34915070Read More
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Pissarra J, Pagniez J, Petitdidier E, Séveno M, Vigy O, Bras-Gonçalves R, Lemesre JL, Holzmuller P. Proteomic Analysis of the Promastigote Secretome of Seven Leishmania Species. J Proteome Res. 2022 Jan 7;21(1):30-48. doi: 10.1021/acs.jproteome.1c00244. Epub 2021 Nov 22. PubMed PMID: 34806897Read More
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Healey RD, Saied EM, Cong X, Karsai G, Gabellier L, Saint Paul J, Del Nero E, Jeannot S, Drapeau M, Fontanel S, Maurel D, Basu S, Leyrat C, Golebiowski J, Bossis G, Bechara C, Hornemann T, Arenz C, Granier S. Discovery and mechanism of action of small molecule inhibitors of ceramidases. Angew Chem Int Ed Engl. 2022 Jan 10;61(2):e202109967. doi: 10.1002/anie.202109967. Epub 2021 Nov 25 PubMed PMID: 34668624Read More
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Al Awabdh S, Donneger F, Goutierre M, Séveno M, Vigy O, Weinzettl P, Russeau M, Moutkine I, Lévi S, Marin P, Poncer JC. Gephyrin interacts with the K-Cl co-transporter KCC2 to regulate its surface expression and function in cortical neurons. J Neurosci. 2022 Jan 12;42(2):166-182. doi: 10.1523/JNEUROSCI.2926-20.2021. Epub 2021 Nov 22. PubMed PMID: 34810232Read More
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Delaby C, Alcolea D, Hirtz C, Vialaret J, Kindermans J, Morichon L, Fortea J, Belbin O, Gabelle A, Blennow K, Zetterberg H, Lleó A, Lehmann S. Blood amyloid and tau biomarkers as predictors of cerebrospinal fluid profiles. J Neural Transm (Vienna). 2022 Feb;129(2):231-237. doi: 10.1007/s00702-022-02474-9. Epub 2022 Feb 15. PubMed PMID: 35169889Read More
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Pernin V, Bec N, Beyze A, Bourgeois A, Szwarc I, Champion C, Chauvin A, Rene C, Mourad G, Merville P, Visentin J, Perrochia H, Couzi L, Larroque C, Le Quintrec M. IgG3 donor-specific antibodies with a proinflammatory glycosylation profile may be associated with the risk of antibody-mediated rejection after kidney transplantation. Am J Transplant. 2022 Mar;22(3):865-875. doi: 10.1111/ajt.16904. Epub 2021 Dec 18. PubMed PMID: 34863025Read More
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Lambey P, Otun O, Cong X, Hoh F, Brunel L, Verdié P, Grison CM, Peysson F, Jeannot S, Durroux T, Bechara C, Granier S, Leyrat C. Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins. Elife. 2022 Mar 21;11:e72555. doi: 10.7554/eLife.72555. PubMed PMID: 35311641Read More
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Volpato M, Vialaret J, Hirtz C, Petit A, Suehs C, Patarin J, Matzner-Lober E, Vachier I, Molinari N, Bourdin A, Charriot J. Rheology predicts sputum eosinophilia in patients with muco-obstructive lung diseases. Biochem Biophys Res Commun. 2022 Sep 24;622:64-71. doi: 10.1016/j.bbrc.2022.07.025. Epub 2022 Jul 11. PubMed PMID: 35843096Read More
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Dos Santos Morais R, Santo PE, Ley M, Schelcher C, Abel Y, Plassart L, Deslignière E, Chagot ME, Quinternet M, Paiva ACF, Hessmann S, Morellet N, M F Sousa P, Vandermoere F, Bertrand E, Charpentier B, Bandeiras TM, Plisson-Chastang C, Verheggen C, Cianférani S, Manival X. Deciphering cellular and molecular determinants of human DPCD protein in complex with RUVBL1/RUVBL2 AAA-ATPases. J Mol Biol. 2022 Oct 15;434(19):167760. doi: 10.1016/j.jmb.2022.167760. Epub 2022 Jul 25. PubMed PMID: 35901867Read More
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Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P. Structure of the vasopressin hormone-V2 receptor-β-arrestin1 ternary complex. Sci Adv. 2022 Sep 2;8(35):eabo7761. doi: 10.1126/sciadv.abo7761. Epub 2022 Sep 2. PubMed PMID: 36054364Read More
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Denis V, Cassagnard N, Del Rio M, Cornillot E, Bec N, Larroque C, Jeanson L, Jarlier M, Combès E, Robert B, Gongora C, Martineau P, Dariavach P. Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells. PLoS One. 2022 Sep 14;17(9):e0274390. doi: 10.1371/journal.pone.0274390. PubMed PMID: 36103569Read More
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SLX4 assembles nuclear condensates that compartmentalize the SUMO-RNF4 pathway and drive DNA repair.
Alghoul E, Paloni M, Arato Takedachi A, Urbach S, Barducci A, Gaillard PH, Basbous J, Constantinou A. SLX4 assembles nuclear condensates that compartmentalize the SUMO-RNF4 pathway and drive DNA repair. BioXriv. 2022 Sept 20 DOI: 10.1101/2022.09.20.508711Read More -
Lebdy R, Canut M, Patouillard J, Cadoret JC, Letessier A, Ammar J, Basbous J, Urbach S, Miotto B, Constantinou A, Abou Merhi R, Ribeyre C. GNL3 regulates replication origin firing and protects stalled replication forks. BioXriv. 2022 Oct 30 DOI: 10.1101/2022.10.27.514025Read More
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Alle Q, Le Borgne E, Bensadoun P, Lemey C, Béchir N, Gabanou M, Estermann F, Bertrand-Gaday C, Pessemesse L, Toupet K, Desprat R, Vialaret J, Hirtz C, Noël D, Jorgensen C, Casas F, Milhavet O, Lemaitre JM. A single short reprogramming early in life initiates and propagates an epigenetically related mechanism improving fitness and promoting an increased healthy lifespan. Aging Cell. 2022 Nov;21(11):e13714. doi: 10.1111/acel.13714. Epub 2022 Oct 17. PubMed PMID: 36251933Read More
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Gruszczyk J, Grandvuillemin L, Lai-Kee-Him J, Paloni M, Savva CG, Germain P, Grimaldi M, Boulahtouf A, Kwong HS, Bous J, Ancelin A, Bechara C, Barducci A, Balaguer P, Bourguet W. Cryo-EM structure of the agonist-bound Hsp90-XAP2-AHR cytosolic complex. Nat Commun. 2022 Nov 16;13(1):7010. doi: 10.1038/s41467-022-34773-w. PubMed PMID: 36385050Read More
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Sparvoli D, Delabre J, Penarete-Vargas DM, Kumar Mageswaran S, Tsypin LM, Heckendorn J, Theveny L, Maynadier M, Mendonça Cova M, Berry-Sterkers L, Guérin A, Dubremetz JF, Urbach S, Striepen B, Turkewitz AP, Chang YW, Lebrun M.. An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma. EMBO J. 2022 Nov 17;41(22):e111158. doi: 10.15252/embj.2022111158. Epub 2022 Oct 17. PubMed PMID: 36245278Read More
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Mohaupt P, Roucou X, Delaby C, Vialaret J, Lehmann S, Hirtz C. The alternative proteome in neurobiology. Front Cell Neurosci. 2022 Nov 17;16:1019680. doi: 10.3389/fncel.2022.1019680. PubMed PMID: 36467612Read More
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Mohaupt P, Pons ML, Vialaret J, Delaby C, Hirtz C, Lehmann S. β-Synuclein as a candidate blood biomarker for synaptic degeneration in Alzheimer's disease. Alzheimers Res Ther. 2022 Nov 30;14(1):179. doi: 10.1186/s13195-022-01125-1. PubMed PMID: 36451155Read More
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Gomes AR, Marin-Menendez A, Adjalley SH, Bardy C, Cassan C, Lee MCS, Talman AM. A transcriptional switch controls sex determination in Plasmodium falciparum. Nature. 2022 Dec;612(7940):528-533. doi: 10.1038/s41586-022-05509-z. Epub 2022 Dec 7. PubMed PMID: 36477538Read More
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Picard AL M, Leblay F, Cassan C, Willemsen A, Bauffe F, Decourcelle M, Demange A, Bravo G I. The non-neutral, multi-level, phenotypic impact of synonymous mutations revealed through heterologous gene expression in human cells. bioRxiv DOI: 2022.01.07.475042Read More
